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After the 26-week treatment period, the mean percentage of weight reduction from baseline was greater with all doses of cagrilintide (0.34.5 mg, 6.0%10.8%) versus placebo (3.0%)

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Anhedonia (loss of pleasure), induced by ketamine 30 mg/kg reducing sucrose preference over 72 hours, was counteracted by BPC-157 with sustained benefit across multiple days